The BWH research laboratories in the Department of Neurosurgery conduct both basic science research and clinical research to explore a range of complex neurological diseases, such as brain tumors, spinal disorders, stroke, and epilepsy. The aim of our research is to investigate the underlying risks, treatment strategies, and outcomes associated with these diseases and translate new findings to design and optimize neurosurgical treatments for each of our patients. Our faculty and scientists apply state-of-the-art techniques and technologies in imaging, bioinformatics, and genetics to take on an integrated, multi-disciplinary approach in their research activities. Our Department works collaboratively on various research projects, as well as with other local, national and international partnering institutes.
Research areas and group include:
- Brain Immunology
- Disease Risk Prediction
- Epilepsy
- Molecular and Cellular Neurosurgical Oncology
- Neuroapoptosis
- Neuro-epidemiology
- Neurosurgical Oncology
- Neurotrauma
- Spinal Cord Injury and Neural Stem Cells
- Stroke
- Surgical Brain Mapping
- Surgical Molecular Imaging
Please read further below to find more specific information about each laboratory's research efforts in the Department of Neurosurgery at Brigham and Women's Hospital.
 | DIRECTOR: Nathalie Agar, Ph.D. FOCUS: Studying accurate molecular diagnosis and prognosis prognosis for clinical and surgical applications MORE INFO: Surgical Molecular Imaging Laboratory
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 | DIRECTOR: William (Stan) Anderson, M.D., Ph.D. FOCUS: Studying the time and spatial evolution of seizures and effects of therapeutic interventions, such as drug delivery and electrical stimulation
MORE INFO: Epilepsy Research Laboratory
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 | DIRECTOR: Peter M. Black, M.D., Ph.D. FOCUS: Studying a broad range of neurosurgical oncology issues including basic questions of tumor behavior and biology
MORE INFO: Neurosurgical Oncology Laboratory
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 | DIRECTOR: Elizabeth Claus, M.D., Ph.D. FOCUS: Studying cancer epidemiology and statistical genetics with an emphasis on the development of risk models for tumors of the central nervous system
MORE INFO: Neuro-Epidemiology Laboratory
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 | DIRECTOR: Arthur L. Day, M.D. FOCUS: Studying the basic mechanisms for stroke, both hemorrhagic and ischemic, with the goal of discovering novel approaches and protectant strategies of these injuries MORE INFO: Stroke Laboratory
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 | DIRECTOR: Rose Du, M.D., Ph.D. FOCUS: Studying the role of genetics in stroke and other cerebrovascular diseases
MORE INFO: Stroke Laboratory
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DIRECTOR: Alexandra Golby, M.D.
FOCUS: Studying advanced structural and functional MRI and brain electrophysiology as tools to develop better surgical treatment for patients with brain tumors and epilepsy
MORE INFO: Surgical Brain Mapping Laboratory
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| DIRECTOR: Bruce Kristal, Ph.D. FOCUS: Studying mitochondrial roles in acute neurological injury, profiling personalized risk analysis, and informatics analysis of clinical and biochemical data sets MORE INFO: The Kristal Lab
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 | DIRECTOR: Lois Lampson, Ph.D. FOCUS: Studying ways to improve the immune response of the body to protect against infections and tumors MORE INFO: Brain Immunology Laboratory
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| DIRECTOR: Yang (Ted) D. Teng, M.D., Ph.D. FOCUS: Studying the molecular mechanisms that enhance strategies to treat challenging issues of spinal cord injuries, as well neurodegenerative diseases MORE INFO: Spinal Cord Injury and Stem Cell Biology Laboratory
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DIRECTOR: Xin Wang, Ph.D. FOCUS: Identification of candidate therapeutics and potential targets for therapeutic intervention in neurodegenerative disorders, including Stroke, Huntington's Disease, and Amyotrophic Lateral Sclerosis MORE INFO: Neuroapoptosis Drug Discovery Laboratory
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Rohit Malhotra
This page was last modified on 7/16/2010